5-Chloroindoline → HCID 178477848, compound

HRID 1453557Notes

Reaction equation

HRID 1453557 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([NH:6][CH:7]=[N:8]2)=[C:4](Cl)[N:3]=1.[Cl:12][C:13]1[CH:14]=[C:15]2[C:19](=[CH:20][CH:21]=1)[NH:18][CH2:17][CH2:16]2>C(O)CCC>[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][NH:8]2)=[C:4]([N:18]2[C:19]3[C:15](=[CH:14][C:13]([Cl:12])=[CH:21][CH:20]=3)[CH2:16][CH2:17]2)[N:3]=1

Participants

4

Reactant 2

HCID 1175965-ChloroindolineHCID 53244122,6-Dichloropurine

Product 1

HCID 178477848HCID 178477848, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

The same procedure as in stage 1 of Example 1 is carried out, starting from 756 mg of 2,6-dichloro-purine, 12 ml of butanol and 737 mg of 5-chloro-2,3-dihydro-1H-indole.

Sources & evidence

ORD record
ord-1abfab7166ce4af6920b5416996139b9
Source dataset
uspto-grants-2009_01
Patent number
US07476670B2

Reaction notes

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