反应详情

567 mg of 2,6-dichloropurine, 6 ml of butanol and 617 mg of 5,6-dichlorobenzimidazole are mixed and brought to a temperature of 100° C. for approximately 24 hours. The mixture is allowed to return to ambient temperature. Partial drying, washing with isopropanol and drying under vacuum at 50° C. are carried out, and 548 mg of expected product are obtained, in the form of gray/black-colored crystals.

1. customto return to ambient temperature
2. customPartial drying
3. washwashing with isopropanol
4. customdrying under vacuum at 50° C.