HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1453586Generated: October 29, 2026
HCID 178478376, compound → HCID 178521609, compound
https://huagongshe.com/reaction/1453586
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 178478376 | HCID 178478376 | — |
| Reactant | HCID 178511715 | HCID 178511715 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 178521609 | HCID 178521609 | 17.4% |
Reaction Steps
200 mg of product obtained in stage 1 above are mixed with 3 ml of DMSO and 586 mg (5 equivalents) of trans-4-aminocyclohexanol, and the mixture is then heated at 120° C. for approximately 4 days. The mixture is allowed to return to ambient temperature. Purification is carried out by chromatography on silica with a CH2Cl2-MeOH—NH4OH: 85-15-1.5 mixture for eluent. 45 mg of expected product are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07476670B2 |
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| Source dataset | uspto-grants-2009_01 |
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| ORD ID | ord-d59e57d047714f069b9e356b84cd853b |
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| Source note | uspto-grants-2009_01 |
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