反应详情

温度

100 °C

The same procedure as in stage 1 of Example 1 is carried out, mixing 378 mg of 2,6-dichloropurine, 10 ml of butanol and 0.32 of dimethylindoline. The mixture is heated at 100° C. for approximately 5 hours and allowed to return to ambient temperature. Partial drying and washing with isopropanol are carried out. The product is dried and 423 mg of expected product are thus obtained.

1. customto return to ambient temperature
2. customPartial drying
3. washwashing with isopropanol
4. customThe product is dried