2-Methyl-4-nitroaniline → 2-Methyl-4-nitrophenyl isocyanate

Participants

Reaction Steps

7.50 g (49.3 mmol) 2-methyl-4-nitro-aniline are combined with 7.20 ml (59.2 mmol) diphosgene in 200 ml of toluene and refluxed for 2 h with stirring. The reaction mixture is evaporated down i. vac., the residue is twice taken up in toluene and evaporated down completely i. vac. The residue is further reacted without any further purification.

Provenance & Evidence