HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-1-butanol → HCID 69054781, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-1-butanol | HCID 13569 | — |
| Reactant | 2-Methyl-4-nitrophenyl isocyanate | HCID 4296456 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 69054781 | HCID 69054781 | — |
Reaction Steps
17.8 g (0.10 mol) 4-isocyanato-3-methyl-1-nitro-benzene are placed in 750 ml of toluene and a solution of 11.7 ml (0.10 mol) 4-chloro-butan-1-ol in 50 ml of toluene is added dropwise. Then the reaction mixture is heated for 16 hours to 75° C., then evaporated down i. vac. and twice taken up with toluene and concentrated by evaporation completely i. vac. The residue is purified by recrystallisation from cyclohexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07476663B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-c739a30a17c14ce2bc65c1fc0de2d3f7 |
| Source note | uspto-grants-2009_01 |