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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1453699Generated: October 27, 2026

1-(2-Bromoethoxy)-4-chlorobenzene → (5-Chloro-3-{3-[2-(4-chloro-phenoxy)-ethyl]-4-oxo-3,4-dihydro-phthalazin-1-yl}-2-methyl-indol-1-yl)-acetic acid

https://huagongshe.com/reaction/1453699

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Bromoethoxy)-4-chlorobenzeneHCID 74854—
Reactanttert-butyl 2-(5-chloro-3-(4-hydroxyphthalazin-1-yl)-2-methyl-1H-indol-1-yl)acetateHCID 58247168—
Product(5-Chloro-3-{3-[2-(4-chloro-phenoxy)-ethyl]-4-oxo-3,4-dihydro-phthalazin-1-yl}-2-methyl-indol-1-yl)-acetic acidHCID 59753850—

Reaction Steps

The title compound was prepared from the product of example 16, step c) and 1-(2-bromo-ethoxy)-4-chloro-benzene using the procedure described in example 14. MS: ESI (negative): 520, 522 (M−H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07476667B2
Source datasetuspto-grants-2009_01
ORD IDord-2cf24043381045f8aafd3a4084ca00bb
Source noteuspto-grants-2009_01