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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1453706Generated: October 27, 2026

Ethyl bromoacetate → [3-(2-Ethoxycarbonylmethyl-1,1-dioxo-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl)-2-methyl-indol-1-yl]-acetic acid

https://huagongshe.com/reaction/1453706

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl bromoacetateHCID 7748—
Reactant[3-(1,1-Dioxo-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl)-2-methyl-indol-1-yl]-acetic acid tert-butyl esterHCID 67317115—
Product[3-(2-Ethoxycarbonylmethyl-1,1-dioxo-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl)-2-methyl-indol-1-yl]-acetic acidHCID 59753828—

Reaction Steps

The title compound was prepared by the method described for example 14 using the product from example 3, step c) and ethyl bromoacetate. MS: ESI (negative): 441 (N−H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07476667B2
Source datasetuspto-grants-2009_01
ORD IDord-2a10d627c94344bda9a08ac15b8806bc
Source noteuspto-grants-2009_01