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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1453714Generated: October 31, 2026

2-(Bromomethyl)-1,3-benzothiazole → [3-(2-Benzothiazol-2-ylmethyl-1,1-dioxo-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl)-5-methyl-indol-1-yl]-acetic acid

https://huagongshe.com/reaction/1453714

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Bromomethyl)-1,3-benzothiazoleHCID 2776258—
Reactant[3-(1,1-Dioxo-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl)-5-methyl-indol-1-yl]-acetic acid tert-butyl esterHCID 67317704—
Product[3-(2-Benzothiazol-2-ylmethyl-1,1-dioxo-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl)-5-methyl-indol-1-yl]-acetic acidHCID 59753800—

Reaction Steps

The title compound was prepared by the method described for example 14 using the product from example 2, step c) and 2-bromomethyl-benzothiazole. MS: ESI (negative): 502 (M-H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07476667B2
Source datasetuspto-grants-2009_01
ORD IDord-ff18be5d96244d949a5f5acf37aad144
Source noteuspto-grants-2009_01