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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1453722Generated: October 25, 2026

(2-Bromopropyl)benzene → {5-Methoxy-3-[2-(1-methyl-2-phenyl-ethyl)-1,1-dioxo-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl]-indol-1-yl}-acetic acid

https://huagongshe.com/reaction/1453722

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Bromopropyl)benzeneHCID 102754—
Reactant[3-(1,1-Dioxo-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl)-5-methoxy-indol-1-yl]-acetic acid tert-butyl esterHCID 67316901—
Product{5-Methoxy-3-[2-(1-methyl-2-phenyl-ethyl)-1,1-dioxo-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl]-indol-1-yl}-acetic acidHCID 59753808—

Reaction Steps

The title compound was prepared by the method described for example 14 using the product from example 4, step c) and (2-bromo-propyl)-benzene. MS: ESI (negative): 489 (M−H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07476667B2
Source datasetuspto-grants-2009_01
ORD IDord-4bb2bfcd4ccc41c8bf906465be185dfb
Source noteuspto-grants-2009_01