HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Bromomethyl)benzonitrile → {3-[2-(4-Cyano-benzyl)-1,1-dioxo-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl]-5-methoxy-indol-1-yl}-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Bromomethyl)benzonitrile | HCID 86996 | — |
| Reactant | [3-(1,1-Dioxo-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl)-5-methoxy-indol-1-yl]-acetic acid tert-butyl ester | HCID 67316901 | — |
| Product | {3-[2-(4-Cyano-benzyl)-1,1-dioxo-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl]-5-methoxy-indol-1-yl}-acetic acid | HCID 59753803 | — |
Reaction Steps
The title compound was prepared by the method described for example 14 using the product from example 4, step c) and 4-cyanobenzyl bromide. MS: ESI (negative): 486 (M−H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07476667B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-e8cc01fc05294e23a5d4df58d1a920b1 |
| Source note | uspto-grants-2009_01 |