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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1453807Generated: November 1, 2026

Nicotinic acid, hydrazide → 3-(4-Methyl-5-(methylsulfonyl)-4H-1,2,4-triazol-3-yl)pyridine

https://huagongshe.com/reaction/1453807

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNicotinic acid, hydrazideHCID 11112—
Reactant4-(4-Methyl-5-(methylsulfonyl)-4H-1,2,4-triazol-3-yl)pyridineHCID 22151477—
Product3-(4-Methyl-5-(methylsulfonyl)-4H-1,2,4-triazol-3-yl)pyridineHCID 46928334—

Reaction Steps

The title compound was prepared analogously to 4-[4-methyl-5-(methylsulfonyl)-4H-1,2,4-triazol-3-yl]pyridine as described herein, via the corresponding sequence consisting of the corresponding steps, by starting from nicotinohydrazide instead of isonicotinohydrazide. 1H NMR: 3.59 (s, 3H), 3.99 (s, 3H), 7.52 (m, 1H), 8.02 (dt, 1H), 8.83 (dd, 1H), 8.91 (m, 1H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07476684B2
Source datasetuspto-grants-2009_01
ORD IDord-34d846db096d4ff39a7df60442d4a5dc
Source noteuspto-grants-2009_01