Ammonium Chloride → HCID 178439601, compound

Participants

Reaction Steps

Ammonium chloride (155 mg, 2.9 mmol) was added to a solution of 4-benzyl-3-propyl-3,4-dihydro-2H-5-pyrrolyl methyl ether (0.67 g, 2.9 mmol) in ethanol (15 ml) and the mixture was heated to reflux for 4 hours. The reaction mixture was filtered and the filtrate was distilled off under reduced pressure. The residue was crystallized from ethyl acetate to yield the title compound (440 mg) as a white crude product. 1H-NMR (DMSO-d6) δ(ppm) 0.62 (3H, t, J=7.2 Hz), 0.87-1.20 (4H, m), 2.01-2.15 (1H, m), 2.72-2.85 (1H, m), 2.88-2.98 (1H, m), 3.05-3.25 (1H, m), 3.50-3.62 (1H, m), 7.19-7.40 (5H, m)

Provenance & Evidence