tert-Butyl 4'-(bromomethyl)biphenyl-2-carboxylate → Ethyl 1-[(2'-t-butoxycarbonylbiphenyl-4-yl)methyl]-2-butyl-4-(1-hydroxy-1-methylethyl)imidazole-5-carboxylate

HRID 145410Notes

Reaction equation

HRID 145410 reaction equation
[Br:19][CH2:20][c:21]1[cH:22][cH:23][c:24](-[c:27]2[c:28]([C:33](=[O:34])[O:35][C:36]([CH3:37])([CH3:38])[CH3:39])[cH:29][cH:30][cH:31][cH:32]2)[cH:25][cH:26]1.[CH2:1]([CH2:2][CH2:3][CH3:4])[c:5]1[nH:6][c:7]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[c:8]([C:10]([CH3:11])([CH3:12])[OH:13])[n:9]1>>[CH2:1]([CH2:2][CH2:3][CH3:4])[c:5]1[n:6]([CH2:20][c:21]2[cH:22][cH:23][c:24](-[c:27]3[c:28]([C:33](=[O:34])[O:35][C:36]([CH3:37])([CH3:38])[CH3:39])[cH:29][cH:30][cH:31][cH:32]3)[cH:25][cH:26]2)[c:7]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[c:8]([C:10]([CH3:11])([CH3:12])[OH:13])[n:9]1

Participants

3

Reactant 2

HCID 9906257tert-Butyl 4'-(bromomethyl)biphenyl-2-carboxylateHCID 178441635HCID 178441635, compound

Product 1

HCID 10744537Ethyl 1-[(2'-t-butoxycarbonylbiphenyl-4-yl)methyl]-2-butyl-4-(1-hydroxy-1-methylethyl)imidazole-5-carboxylate

Sources & evidence

ORD record
ord-f60d9c531d4042a3b3c0a395ef487eb2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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