Acetic Acid → HCID 72819808, compound

Participants

Reaction Steps

A solution of 1-(4-fluoro-phenyl)-2-pyridin-4-yl-ethanone (6.45 g, prepared according to the method described for Reference Example 11 in the specification of International Patent Application No. WO98/56788) in acetic acid (50 ml) was treated with a solution of sodium nitrite (4.14 g) in water (30 ml) at 10° C. The reaction mixture was stirred at room temperature for 16 hours then treated with water (150 ml) and then filtered to give the title compound as a white solid.

Provenance & Evidence