Acetyl chloride → N-acetyl-3'-amino-5-formyl-6-methoxy-biphenyl-3-sulfonamide

HRID 1454537Notes

Reaction equation

[NH2:1][C:2]1[CH:3]=[C:4]([C:8]2[C:13]([O:14][CH3:15])=[C:12]([CH:16]=[O:17])[CH:11]=[C:10]([S:18]([NH2:21])(=[O:20])=[O:19])[CH:9]=2)[CH:5]=[CH:6][CH:7]=1.[C:22](Cl)(=[O:24])[CH3:23]>>[C:22]([NH:21][S:18]([C:10]1[CH:9]=[C:8]([C:4]2[CH:5]=[CH:6][CH:7]=[C:2]([NH2:1])[CH:3]=2)[C:13]([O:14][CH3:15])=[C:12]([CH:16]=[O:17])[CH:11]=1)(=[O:19])=[O:20])(=[O:24])[CH3:23]

Participants

Reactant 2

HCID 6367Acetyl chloride

HCID 866077123'-Amino-5-formyl-6-methoxy-biphenyl-3-sulfonamide

Product 1

HCID 86607721N-acetyl-3'-amino-5-formyl-6-methoxy-biphenyl-3-sulfonamide

Procedure

Proceeding as in Reference 21, but substituting 3′-amino-5-formyl-6-methoxy-biphenyl-3-sulfonamide and acetyl chloride, gave N-acetyl-3′-amino-5-formyl-6-methoxy-biphenyl-3-sulfonamide.

Sources & evidence

ORD record: ord-2e04378f34244a0aa6487a1c8066b2cb
Source dataset: uspto-grants-2009_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07479502B2

Reaction notes

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