Phenylacetyl chloride → 5-formyl-6-methoxy-3'-nitro-N-(2-phenylacetyl)-biphenyl-3-sulfonamide

HRID 1454540Notes

Reaction equation

[CH:1]([C:3]1[CH:4]=[C:5]([S:20]([NH2:23])(=[O:22])=[O:21])[CH:6]=[C:7]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([N+:17]([O-:19])=[O:18])[CH:12]=2)[C:8]=1[O:9][CH3:10])=[O:2].[C:24]1([CH2:30][C:31](Cl)=[O:32])[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[CH:1]([C:3]1[CH:4]=[C:5]([S:20]([NH:23][C:31](=[O:32])[CH2:30][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)(=[O:22])=[O:21])[CH:6]=[C:7]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([N+:17]([O-:19])=[O:18])[CH:12]=2)[C:8]=1[O:9][CH3:10])=[O:2]

Participants

Reactant 2

HCID 7679Phenylacetyl chloride

HCID 866077105-Formyl-6-methoxy-3'-nitro-biphenyl-3-sulfonamide

Product 1

HCID 866077245-formyl-6-methoxy-3'-nitro-N-(2-phenylacetyl)-biphenyl-3-sulfonamide

Procedure

Proceeding as in Reference 21, but substituting 5-formyl-6-methoxy-3′-nitro-biphenyl-3-sulfonamide and 2-phenylacetyl chloride, gave 5-formyl-6-methoxy-3′-nitro-N-(2-phenylacetyl)-biphenyl-3-sulfonamide.

Sources & evidence

ORD record: ord-f4145dc74463434c8448494e3a3c3914
Source dataset: uspto-grants-2009_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07479502B2

Reaction notes

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