Valeryl chloride → HCID 67098983, compound

HRID 1454624Notes

Reaction equation

[NH2:1][C:2]1[CH:17]=[CH:16][C:15]([F:18])=[CH:14][C:3]=1[NH:4][C:5]1[CH:10]=[CH:9][C:8]([CH2:11][CH2:12][OH:13])=[CH:7][CH:6]=1.[C:19](Cl)(=[O:24])[CH2:20][CH2:21][CH2:22][CH3:23]>>[C:19]([O:13][CH2:12][CH2:11][C:8]1[CH:9]=[CH:10][C:5]([N:4]2[C:3]3[CH:14]=[C:15]([F:18])[CH:16]=[CH:17][C:2]=3[N:1]=[C:14]2[CH2:3][CH2:2][CH2:17][CH3:16])=[CH:6][CH:7]=1)(=[O:24])[CH2:20][CH2:21][CH2:22][CH3:23]

Participants

Reactant 2

HCID 61186Valeryl chloride

HCID 21875975HCID 21875975, compound

Product 1

HCID 67098983HCID 67098983, compound

Procedure

The title compound was prepared according to the procedure described in step 5 of Example 1 from 2-[4-(2-amino-5-fluoroanilino)phenyl]ethanol (step 2) and pentanoyl chloride.

Sources & evidence

ORD record: ord-6381d34008e74e41823f64eb001d7f9d
Source dataset: uspto-grants-2009_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07479564B2

Reaction notes

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