4-Aminophenethyl alcohol → HCID 86613467, compound
Reaction equation
Cl[C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[N+:10]([O-:12])=[O:11])[C:5]#[N:6].NC1C=CC(C[CH2:21][OH:22])=CC=1>>[OH:22][CH2:21][CH2:5][C:4]1[CH:3]=[CH:2][C:9]([NH:10][OH:12])=[CH:8][CH:7]=1.[N+:10]([C:9]1[CH:2]=[CH:3][C:4]([C:5]#[N:6])=[CH:7][CH:8]=1)([O-:12])=[O:11]Participants
3
Procedure
The title compound was prepared according to the procedure described in step 3 of Example 1 from 3-chloro-4-nitrobenzonitrile (Tsuji, K. Chem. Pharm. Bull. 1992, 40, 2399) and 4-aminophenylethyl alcohol.
Sources & evidence
- ORD record
- ord-de19dae0d865459b99843d2594126e5b
- Source dataset
- uspto-grants-2009_01
- Patent number
- US07479564B2
Reaction notes
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