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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1454686Generated: October 25, 2026

2,4-Dichloro-5-nitrobenzotrifluoride → (2r)-1-(4-{[5-Chloro-2-nitro-4-(trifluoromethyl)phenyl]amino}phenyl)-2-propanol

https://huagongshe.com/reaction/1454686

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-Dichloro-5-nitrobenzotrifluorideHCID 621179—
Reactant(2R)-1-(4-aminophenyl)-2-propanolHCID 67099545—
Product(2r)-1-(4-{[5-Chloro-2-nitro-4-(trifluoromethyl)phenyl]amino}phenyl)-2-propanolHCID 67099586—

Reaction Steps

The title compound was prepared according to the procedure described in step 1 of Example 162 from 2,4-dichloro-5-nitrobenzotrifluoride and (2R)-1-(4-aminophenyl)-2-propanol (step 2 of Example 249).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07479564B2
Source datasetuspto-grants-2009_01
ORD IDord-b9c213b3a6f74e39b16e4e486ce82435
Source noteuspto-grants-2009_01