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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1454707Generated: November 2, 2026

Isoquinoline-5-sulfonamide → 2-{4-[6-Chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-YL]phenyl}ethyl-5-isoquinolinylsulfonylcarbamate

https://huagongshe.com/reaction/1454707

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsoquinoline-5-sulfonamideHCID 9837177—
Reactant2-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl phenyl carbonateHCID 21876409—
Product2-{4-[6-Chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-YL]phenyl}ethyl-5-isoquinolinylsulfonylcarbamateHCID 21876099—

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 243 from 2-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl phenyl carbonate and 5-isoquinolinylsulfonamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07479564B2
Source datasetuspto-grants-2009_01
ORD IDord-5de12c7181e447ffbc9a17d408107fcc
Source noteuspto-grants-2009_01