2-Hydroxyisobutyric acid → HCID 21875955, compound

HRID 1454732Notes

Reaction equation

HRID 1454732 reaction equation
[OH:1][C:2]([CH3:7])([CH3:6])[C:3](O)=O.[Cl:8][C:9]1[CH:10]=[C:11]([NH:20][C:21]2[CH:26]=[CH:25][C:24]([CH2:27][CH2:28][Cl:29])=[CH:23][CH:22]=2)[C:12]([NH2:19])=[CH:13][C:14]=1[C:15]([F:18])([F:17])[F:16]>>[Cl:8][C:9]1[C:14]([C:15]([F:16])([F:17])[F:18])=[CH:13][C:12]2[N:19]=[C:3]([C:2]([OH:1])([CH3:7])[CH3:6])[N:20]([C:21]3[CH:26]=[CH:25][C:24]([CH2:27][CH2:28][Cl:29])=[CH:23][CH:22]=3)[C:11]=2[CH:10]=1

Participants

3

Reactant 2

HCID 116712-Hydroxyisobutyric acidHCID 67099949HCID 67099949, compound

Product 1

HCID 21875955HCID 21875955, compound

Procedure

The title compound was prepared according to the procedure described in Example 339, step 3 & Example 1, step 5 from 2-hydroxyisobutyric acid and 4-chloro-N2-[4-(2-chloroethyl)phenyl]-5-(trifluoromethyl)-1,2-benzenediamine.

Sources & evidence

ORD record
ord-8579d6ba6d8149718ea13c8ab8285f1f
Source dataset
uspto-grants-2009_01
Patent number
US07479564B2

Reaction notes

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