HCID 87681742, compound → HCID 87683750, compound

HRID 1454748Notes

Reaction equation

HRID 1454748 reaction equation
[K].[C:2]([O:6][C:7](=[O:13])[CH:8]([C:11]#[N:12])[CH:9]=[O:10])([CH3:5])([CH3:4])[CH3:3].[CH2:14]([P+:18]([CH2:27][CH2:28][CH2:29][CH3:30])([CH2:23][CH2:24][CH2:25][CH3:26])[CH2:19][CH2:20][CH2:21][CH3:22])[CH2:15][CH2:16][CH3:17].C(OC(=O)C(C#N)C=O)CCCCCCC>[Cl-].C([P+](CCCC)(CCCC)CCCC)CCC>[CH2:27]([P+:18]([CH2:14][CH2:15][CH2:16][CH3:17])([CH2:19][CH2:20][CH2:21][CH3:22])[CH2:23][CH2:24][CH2:25][CH3:26])[CH2:28][CH2:29][CH3:30].[C:2]([O:6][C:7](=[O:13])[CH:8]([C:11]#[N:12])[CH:9]=[O:10])([CH3:5])([CH3:3])[CH3:4]

Participants

4

Reactant 2

HCID 87681742HCID 87681742, compoundHCID 87683830HCID 87683830, compound

Product 1

HCID 87683750HCID 87683750, compound

Reagents, catalysts & solvents 1

HCID 75311Tetrabutylphosphonium chlorideCatalyst

Procedure

CDP-6 was prepared from 3-oxo-2-cyanopropanoic acid t-butyl ester potassium salt and tetra-n-butylphosphonium chloride similar to the method described above for CDP-1. It was isolated as an orange color oil that crystallized upon standing.

Workup

  1. customIt was isolated as an orange color oil that
  2. customcrystallized

Sources & evidence

ORD record
ord-92fc532b5be340c89982ee52a75edc0b
Source dataset
uspto-grants-2009_01
Patent number
US07482113B2

Reaction notes

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