HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-p-toluenesulfochloride → 3-Chloro-N-[6-(4-fluoro-benzyloxymethyl)-pyridin-2-yl]-4-methyl-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-p-toluenesulfochloride | HCID 259744 | — |
| Reactant | 6-(4-Fluoro-benzyloxymethyl)-pyridin-2-ylamine | HCID 68845140 | — |
| Product | 3-Chloro-N-[6-(4-fluoro-benzyloxymethyl)-pyridin-2-yl]-4-methyl-benzenesulfonamide | HCID 11668955 | — |
Reaction Steps
This material was prepared in analogy to example 1 from 6-(4-fluoro-benzyloxymethyl)-pyridin-2-ylamine (0.058 g) and 3-chloro-4-methyl-benzenesulfonyl chloride (0.062 g) as a light yellow gum (0.09 g). MS (ESI−): 419.0. ([M−H]−)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07482341B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-93b82e4ce20345cbb7808a6e9400d018 |
| Source note | uspto-grants-2009_01 |