2-Chloro-p-toluenesulfochloride → HCID 11633915, compound

HRID 1454829Notes

Reaction equation

HRID 1454829 reaction equation
[F:1][C:2]([F:19])([F:18])[C:3]1[CH:17]=[CH:16][C:6]([O:7][CH2:8][C:9]2[N:14]=[C:13]([NH2:15])[CH:12]=[CH:11][CH:10]=2)=[CH:5][CH:4]=1.[Cl:20][C:21]1[CH:22]=[C:23]([S:28](Cl)(=[O:30])=[O:29])[CH:24]=[CH:25][C:26]=1[CH3:27]>>[Cl:20][C:21]1[CH:22]=[C:23]([S:28]([NH:15][C:13]2[CH:12]=[CH:11][CH:10]=[C:9]([CH2:8][O:7][C:6]3[CH:16]=[CH:17][C:3]([C:2]([F:1])([F:18])[F:19])=[CH:4][CH:5]=3)[N:14]=2)(=[O:30])=[O:29])[CH:24]=[CH:25][C:26]=1[CH3:27]

Participants

3

Reactant 2

HCID 2597442-Chloro-p-toluenesulfochlorideHCID 68842874HCID 68842874, compound

Product 1

HCID 11633915HCID 11633915, compound

Procedure

This material was prepared in analogy to example 1 from 6-(4-trifluoromethyl-phenoxymethyl)-pyridin-2-ylamine (0.08 g) and 3-chloro-4-methyl-benzenesulfonyl chloride (0.074 g) as an off-white solid (0.105 g). MS (ESI−): 455.2 ([M−H]−).

Sources & evidence

ORD record
ord-f94badca53244beba10f67c160572b5a
Source dataset
uspto-grants-2009_01
Patent number
US07482341B2

Reaction notes

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