3-Chloro-2-methylbenzenesulfonyl chloride → HCID 11568751, compound

HRID 1454830Notes

Reaction equation

HRID 1454830 reaction equation
[F:1][C:2]([F:19])([F:18])[C:3]1[CH:17]=[CH:16][C:6]([O:7][CH2:8][C:9]2[N:14]=[C:13]([NH2:15])[CH:12]=[CH:11][CH:10]=2)=[CH:5][CH:4]=1.[Cl:20][C:21]1[C:22]([CH3:31])=[C:23]([S:27](Cl)(=[O:29])=[O:28])[CH:24]=[CH:25][CH:26]=1>>[Cl:20][C:21]1[C:22]([CH3:31])=[C:23]([S:27]([NH:15][C:13]2[CH:12]=[CH:11][CH:10]=[C:9]([CH2:8][O:7][C:6]3[CH:16]=[CH:17][C:3]([C:2]([F:1])([F:18])[F:19])=[CH:4][CH:5]=3)[N:14]=2)(=[O:29])=[O:28])[CH:24]=[CH:25][CH:26]=1

Participants

3

Reactant 2

HCID 5227343-Chloro-2-methylbenzenesulfonyl chlorideHCID 68842874HCID 68842874, compound

Product 1

HCID 11568751HCID 11568751, compound

Procedure

This material was prepared in analogy to example 1 from 6-(4-trifluoromethyl-phenoxymethyl)-pyridin-2-ylamine (0.08 g) and 3-chloro-2-methyl-benzenesulfonyl chloride (0.074 g) as an off-white solid (0.113 g). MS (ESI−): 455.2 ([M−H]−).

Sources & evidence

ORD record
ord-1341e2c820da4afbb0adb87bd8b0b37d
Source dataset
uspto-grants-2009_01
Patent number
US07482341B2

Reaction notes

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