Piperidine-1-sulfonyl chloride → Piperidine-1-sulfonic acid (5-cyclopropylmethoxymethyl-pyridin-2-yl)-amide

HRID 1454840Notes

Reaction equation

HRID 1454840 reaction equation
[CH:1]1([CH2:4][O:5][CH2:6][C:7]2[CH:8]=[CH:9][C:10]([NH2:13])=[N:11][CH:12]=2)[CH2:3][CH2:2]1.[N:14]1([S:20](Cl)(=[O:22])=[O:21])[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1>>[CH:1]1([CH2:4][O:5][CH2:6][C:7]2[CH:8]=[CH:9][C:10]([NH:13][S:20]([N:14]3[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]3)(=[O:22])=[O:21])=[N:11][CH:12]=2)[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 11298344Piperidine-1-sulfonyl chlorideHCID 621942995-Cyclopropylmethoxymethyl-pyridin-2-ylamine

Product 1

HCID 86604235Piperidine-1-sulfonic acid (5-cyclopropylmethoxymethyl-pyridin-2-yl)-amide

Procedure

This material was prepared in analogy to example 1 from 5-cyclopropylmethoxymethyl-pyridin-2-ylamine (0.089 g) and piperidine-1-sulfonyl chloride (0.142 g) as a light yellow gum (0.027 g). MS (ESI−): 324.2 ([M−H]−)

Sources & evidence

ORD record
ord-5ffa9c4ed31d4de7815e9405b4b75b9c
Source dataset
uspto-grants-2009_01
Patent number
US07482341B2

Reaction notes

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