4-Fluorobenzyl bromide → N-[5-(4-Fluoro-benzyloxymethyl)-6-methyl-pyridin-2-yl]-2,2-dimethyl-propionamide

Participants

Role	Name	HCID	Charge
Reactant	4-Fluorobenzyl bromide	HCID 68021	—
Reactant	N-(5-Hydroxymethyl-6-methyl-pyridin-2-yl)-2,2-dimethyl-propionamide	HCID 68844472	—
Product	N-[5-(4-Fluoro-benzyloxymethyl)-6-methyl-pyridin-2-yl]-2,2-dimethyl-propionamide	HCID 68842559	—

Reaction Steps

This material was prepared in analogy to example 86 step A] from N-(5-hydroxymethyl-6-methyl-pyridin-2-yl)-2,2-dimethyl-propionamide (0.6 g, product of example 112 step B]) and 4-fluorobenzyl bromide (0.56 g) as an orange solid (0.8 g). MS (ESI): 231.3 (MH+).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07482341B2
Source dataset	uspto-grants-2009_01
ORD ID	ord-e921baa26eeb4addada11117b406faf0
Source note	uspto-grants-2009_01