Sodium Hydroxide → 6-[(Methyl-propyl-amino)-methyl]-pyridin-2-ylamine

HRID 1454861Notes

Reaction equation

HRID 1454861 reaction equation
CC(C)(C)C([NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([CH2:12][N:13]([CH3:17])[CH2:14][CH2:15][CH3:16])[N:7]=1)=O.[OH-].[Na+]>>[CH3:17][N:13]([CH2:12][C:8]1[N:7]=[C:6]([NH2:5])[CH:11]=[CH:10][CH:9]=1)[CH2:14][CH2:15][CH3:16]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 68842962HCID 68842962, compound

Product 1

HCID 688429776-[(Methyl-propyl-amino)-methyl]-pyridin-2-ylamine

Procedure

This material was prepared in analogy to example 86 step B] from 2,2-dimethyl-N-{6-[(methyl-propyl-amino)-methyl]-pyridin-2-yl}-propionamide (0.755 g) and 3M aqueous NaOH (5.73 mL) as a brown liquid (0.53 g). MS (ESI): 180.2 (MH+).

Sources & evidence

ORD record
ord-9c46482e722542a4bef4360338816697
Source dataset
uspto-grants-2009_01
Patent number
US07482341B2

Reaction notes

Loading…