HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chloro-p-xylene-2-sulphonyl chloride → 4-Chloro-N-[6-(4-fluoro-benzyloxymethyl)-pyridin-2-yl]-2,5-dimethyl-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chloro-p-xylene-2-sulphonyl chloride | HCID 66618 | — |
| Reactant | 6-(4-Fluoro-benzyloxymethyl)-pyridin-2-ylamine | HCID 68845140 | — |
| Product | 4-Chloro-N-[6-(4-fluoro-benzyloxymethyl)-pyridin-2-yl]-2,5-dimethyl-benzenesulfonamide | HCID 68843301 | — |
Reaction Steps
This material was prepared in analogy to example 1 from 6-(4-fluoro-benzyloxymethyl)-pyridin-2-ylamine (0.058 g) and 4-chloro-2,5-dimethyl-benzenesulfonyl chloride (0.066 g) as a light yellow gum (0.089 g). MS (ESI−): 433.2. ([M−H]−)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07482341B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-3b63c3ba7a4c4765a20780bd9fd814ee |
| Source note | uspto-grants-2009_01 |