3-(Trifluoromethyl)benzenesulfonyl chloride → HCID 86604237, compound

HRID 1454869Notes

Reaction equation

HRID 1454869 reaction equation
[F:1][C:2]([F:19])([F:18])[C:3]1[CH:17]=[CH:16][C:6]([O:7][CH2:8][C:9]2[N:14]=[C:13]([NH2:15])[CH:12]=[CH:11][CH:10]=2)=[CH:5][CH:4]=1.[F:20][C:21]([F:33])([F:32])[C:22]1[CH:23]=[C:24]([S:28](Cl)(=[O:30])=[O:29])[CH:25]=[CH:26][CH:27]=1>>[F:33][C:21]([F:20])([F:32])[C:22]1[CH:23]=[C:24]([S:28]([NH:15][C:13]2[CH:12]=[CH:11][CH:10]=[C:9]([CH2:8][O:7][C:6]3[CH:16]=[CH:17][C:3]([C:2]([F:1])([F:18])[F:19])=[CH:4][CH:5]=3)[N:14]=2)(=[O:29])=[O:30])[CH:25]=[CH:26][CH:27]=1

Participants

3

Reactant 2

HCID 27332503-(Trifluoromethyl)benzenesulfonyl chlorideHCID 68842874HCID 68842874, compound

Product 1

HCID 86604237HCID 86604237, compound

Procedure

This material was prepared in analogy to example 1 from 6-(4-trifluoromethyl-phenoxymethyl)-pyridin-2-ylamine (0.08 g) and 3-(trifluoromethyl)-benzenesulfonyl chloride (0.081 g) as a light yellow gum (0.114 g). MS (ESI−): 475.0 ([M−H]−).

Sources & evidence

ORD record
ord-8cd0861cae524156b18a48e89c6c9fac
Source dataset
uspto-grants-2009_01
Patent number
US07482341B2

Reaction notes

Loading…