HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 5-(2-Fluoro-ethoxymethyl)-6-methyl-pyridin-2-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | N-[5-(2-Fluoro-ethoxymethyl)-6-methyl-pyridin-2-yl]-2,2-dimethyl-propionamide | HCID 86604238 | — |
| Product | 5-(2-Fluoro-ethoxymethyl)-6-methyl-pyridin-2-ylamine | HCID 86233776 | — |
Reaction Steps
This material was prepared in analogy to example 86 step B] from N-[5-(2-Fluoro-ethoxymethyl)-6-methyl-pyridin-2-yl]-2,2-dimethyl-propionamide (0.165 g) and 3M aqueous NaOH (1.23 mL) as an gum (0.174 g) that was used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07482341B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-980289a6aa99450a8c7ae76245de99f2 |
| Source note | uspto-grants-2009_01 |