3-Fluorobenzyl bromide → HCID 68840849, compound

HRID 1454877Notes

Reaction equation

HRID 1454877 reaction equation
[OH:1][CH2:2][C:3]1[N:8]=[C:7]([NH:9][C:10](=[O:15])[C:11]([CH3:14])([CH3:13])[CH3:12])[CH:6]=[CH:5][CH:4]=1.[F:16][C:17]1[CH:18]=[C:19]([CH:22]=[CH:23][CH:24]=1)[CH2:20]Br>>[F:16][C:17]1[CH:18]=[C:19]([CH:22]=[CH:23][CH:24]=1)[CH2:20][O:1][CH2:2][C:3]1[N:8]=[C:7]([NH:9][C:10](=[O:15])[C:11]([CH3:12])([CH3:14])[CH3:13])[CH:6]=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 680073-Fluorobenzyl bromideHCID 21782926N-[6-(Hydroxymethyl)pyridin-2-yl]-2,2-dimethylpropanamide

Product 1

HCID 68840849HCID 68840849, compound

Procedure

This material was prepared in analogy to example 86 step A] from N-(6-hydroxymethyl-pyridin-2-yl)-2,2-dimethyl-propionamide (0.73 g) and 3-fluorobenzyl bromide as a yellow solid(0.66 g). MS (ESI): 317.1 (MH+).

Sources & evidence

ORD record
ord-e38434da4ac14feb948cbb50cb45e579
Source dataset
uspto-grants-2009_01
Patent number
US07482341B2

Reaction notes

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