3-Chlorobenzenesulphonyl chloride → HCID 68841029, compound

HRID 1454882Notes

Reaction equation

HRID 1454882 reaction equation
[F:1][C:2]1[CH:17]=[CH:16][C:5]([CH2:6][O:7][CH2:8][C:9]2[N:14]=[C:13]([NH2:15])[CH:12]=[CH:11][CH:10]=2)=[CH:4][CH:3]=1.[Cl:18][C:19]1[CH:20]=[C:21]([S:25](Cl)(=[O:27])=[O:26])[CH:22]=[CH:23][CH:24]=1>>[Cl:18][C:19]1[CH:20]=[C:21]([S:25]([NH:15][C:13]2[CH:12]=[CH:11][CH:10]=[C:9]([CH2:8][O:7][CH2:6][C:5]3[CH:4]=[CH:3][C:2]([F:1])=[CH:17][CH:16]=3)[N:14]=2)(=[O:27])=[O:26])[CH:22]=[CH:23][CH:24]=1

Participants

3

Reactant 2

HCID 179093-Chlorobenzenesulphonyl chlorideHCID 688451406-(4-Fluoro-benzyloxymethyl)-pyridin-2-ylamine

Product 1

HCID 68841029HCID 68841029, compound

Procedure

This material was prepared in analogy to example 1 from 6-(4-fluoro-benzyloxymethyl)-pyridin-2-ylamine (0.07 g) and 3-chloro-benzenesulfonyl chloride (0.07 g) as a light yellow gum (0.059 g). MS (ESI−): 405.2 ([M−H]−).

Sources & evidence

ORD record
ord-43143ab5304b480e979d6eb6ed570ae0
Source dataset
uspto-grants-2009_01
Patent number
US07482341B2

Reaction notes

Loading…