HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-3-(trifluoromethyl)benzenesulfonyl Chloride → 4-Fluoro-N-[6-(4-fluoro-benzyloxymethyl)-pyridin-2-yl]-3-trifluoromethyl-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-3-(trifluoromethyl)benzenesulfonyl Chloride | HCID 2737549 | — |
| Reactant | 6-(4-Fluoro-benzyloxymethyl)-pyridin-2-ylamine | HCID 68845140 | — |
| Product | 4-Fluoro-N-[6-(4-fluoro-benzyloxymethyl)-pyridin-2-yl]-3-trifluoromethyl-benzenesulfonamide | HCID 68846192 | — |
Reaction Steps
This material was prepared in analogy to example 1 from 6-(4-fluoro-benzyloxymethyl)-pyridin-2-ylamine (0.07 g) and 4-fluoro-3-(trifluoromethyl)-benzenesulfonyl chloride (0.087 g) as alight yellow gum (0.11 g). MS (ESI−): 457.2 ([M−H]−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07482341B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-9a3d91b33d3342838cc07c27e068bd74 |
| Source note | uspto-grants-2009_01 |