HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-3-(trifluoromethyl)benzenesulfonyl Chloride → N-[6-(4-Chloro-benzyloxymethyl)-pyridin-2-yl]-4-fluoro-3-trifluoromethyl-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-3-(trifluoromethyl)benzenesulfonyl Chloride | HCID 2737549 | — |
| Reactant | 6-(4-Chloro-benzyloxymethyl)-pyridin-2-ylamine | HCID 68845104 | — |
| Product | N-[6-(4-Chloro-benzyloxymethyl)-pyridin-2-yl]-4-fluoro-3-trifluoromethyl-benzenesulfonamide | HCID 68845596 | — |
Reaction Steps
This material was prepared in analogy to example 1 from 6-(4-chloro-benzyloxymethyl)-pyridin-2-ylamine (0.08 g) and 4-fluoro-3-(trifluoromethyl)-benzenesulfonyl chloride (0.092g) as a light yellow gum (0.039 g). MS (ESI−): 472.8 ([M−H]−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07482341B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-7174d804faf74439bd5d185ef6bb256f |
| Source note | uspto-grants-2009_01 |