Sodium Hydroxide → HCID 62193320, compound

HRID 1454909Notes

Reaction equation

HRID 1454909 reaction equation
CC(C)(C)C([NH:5][C:6]1[CH:11]=[CH:10][C:9]([CH2:12][O:13][CH2:14][C:15]([F:18])([F:17])[F:16])=[CH:8][N:7]=1)=O.[OH-].[Na+]>>[F:18][C:15]([F:16])([F:17])[CH2:14][O:13][CH2:12][C:9]1[CH:10]=[CH:11][C:6]([NH2:5])=[N:7][CH:8]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 68841205HCID 68841205, compound

Product 1

HCID 62193320HCID 62193320, compound

Procedure

This material was prepared in analogy to example 86 step B] from 2,2-dimethyl-N-[5-(2,2,2-trifluoro-ethoxymethyl)-pyridin-2-yl]-propionamide (0.56 g) and 3M aqueous NaOH (3.87 mL) as a crystalline white solid (0.123 g). MS (ESI): 207.1 (MH+).

Sources & evidence

ORD record
ord-7310d75ec60c49a2a2a82e659ddfeafc
Source dataset
uspto-grants-2009_01
Patent number
US07482341B2

Reaction notes

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