N-chlorosuccinamide → HCID 178461799, compound

Participants

Reaction Steps

The product of Example 3 (0.22 g) was dissolved in AcOH (10 ml), N-chlorosuccinamide (90 mg) added and stirred for 3 h. The volatiles were removed under reduced pressure and the residue purified by reverse phase HPLC with gradient elution in acetonitrile/0.02M ammonium hydroxide (90% to 50% aqueous phase) to yield the title product as a white solid. Yield 0.1 g.

Provenance & Evidence