HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-[(1-Methylpiperidin-4-yl)oxy]aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | N-[3-(1-Methyl-piperidin-4-yloxy)-phenyl]-acetamide | HCID 57444159 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-[(1-Methylpiperidin-4-yl)oxy]aniline | HCID 39202654 | — |
Reaction Steps
A solution of N-[3-(1-Methyl-piperidin-4-yloxy)-phenyl]-acetamide (2.604 g) in absolute ethanol (40 mL) was treated with 37% hydrochloric acid and the solution was heated to reflux for 3 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07482354B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-54107a9315664b5b910ffff5cbf82b3c |
| Source note | uspto-grants-2009_01 |