1H-imidazole-2-carbaldehyde → HCID 57532141, compound
Reaction equation
[NH:1]1[CH:5]=[CH:4][N:3]=[C:2]1[CH:6]=O.Cl.[F:9][CH:10]1[CH2:14][CH2:13][NH:12][CH2:11]1>>[F:9][CH:10]1[CH2:14][CH2:13][N:12]([CH2:6][C:2]2[NH:3][CH:4]=[CH:5][N:1]=2)[CH2:11]1Participants
3
Procedure
The title compound was prepared from 2-imidazolecarboxaldehyde and 3-fluoropyrrolidine hydrochloride using the synthetic procedure described for Intermediate 5.
Sources & evidence
- ORD record
- ord-2fcf75c225474968abf4fde5e24c577c
- Source dataset
- uspto-grants-2009_01
- Patent number
- US07482374B2
Reaction notes
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