1H-imidazole-2-carbaldehyde → 2-((3-Methoxyazetidin-1-yl)methyl)-1H-imidazole
Reaction equation
[NH:1]1[CH:5]=[CH:4][N:3]=[C:2]1[CH:6]=O.Cl.[CH3:9][O:10][CH:11]1[CH2:14][NH:13][CH2:12]1>>[CH3:9][O:10][CH:11]1[CH2:14][N:13]([CH2:6][C:2]2[NH:1][CH:5]=[CH:4][N:3]=2)[CH2:12]1Participants
3
Procedure
The title compound was prepared from 2-imidazolecarboxaldehyde and 3-methoxyazetidine hydrochloride using the synthetic procedure described for Intermediate 5.
Sources & evidence
- ORD record
- ord-7ef831680931483ebd67ff50d45dad0b
- Source dataset
- uspto-grants-2009_01
- Patent number
- US07482374B2
Reaction notes
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