HCID 68914119, compound → HCID 68913248, compound

HRID 1455277Notes

Reaction equation

HRID 1455277 reaction equation
C(C1C=CC(OC2C(OC)=NN(CC(O)=O)C=2CC)=CC=1)#N.[C:23]([C:25]1[C:49]([CH3:50])=[CH:48][C:28]([O:29][C:30]2[C:31]([CH:45]3[CH2:47][CH2:46]3)=[N:32][N:33]([C:35]([CH3:44])([CH3:43])[C:36]([O:38]C(C)(C)C)=[O:37])[CH:34]=2)=[CH:27][C:26]=1[CH3:51])#[N:24]>>[C:23]([C:25]1[C:26]([CH3:51])=[CH:27][C:28]([O:29][C:30]2[C:31]([CH:45]3[CH2:47][CH2:46]3)=[N:32][N:33]([C:35]([CH3:44])([CH3:43])[C:36]([OH:38])=[O:37])[CH:34]=2)=[CH:48][C:49]=1[CH3:50])#[N:24]

Participants

3

Reactant 2

HCID 68914119HCID 68914119, compoundHCID 91006489HCID 91006489, compound

Product 1

HCID 68913248HCID 68913248, compoundYield 66%

Procedure

The title compound (287 mg, 66%) was prepared by a similar method to that described for the acid of step (b) of Example 80 using the ester of step (a) from above as starting material.

Sources & evidence

ORD record
ord-75a2baaf88294f6692a8cb47de52d35c
Source dataset
uspto-grants-2009_01
Patent number
US07482375B2

Reaction notes

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