HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 10113060, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Hydantoin | HCID 10006 | — |
| Reactant | HCID 13126067 | HCID 13126067 | — |
| Reactant | HCID 22392842 | HCID 22392842 | — |
| Product | HCID 10113060 | HCID 10113060 | 39% |
Reaction Steps
5-(aminomethyl)-5-methylhydantoin (109a)(55 mg, 0.31 mmol) was coupled with 4-{[2-(methylthio)-1H-benzimidazol-1-yl]methyl}benzoic acid (108 mg, 0.37 mmol) using general coupling method B to give 50 mg (39%) of the product hydantoin as a TFA salt. MS found: (M+H)+=425.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07482372B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-3a93406c503845a986e2bf113f1c5fe8 |
| Source note | uspto-grants-2009_01 |