3-Chloro-2,4-difluorobenzoic acid → 2,4-Difluoro-3-methoxybenzoic acid

HRID 1455491Notes

Reaction equation

HRID 1455491 reaction equation
Cl[C:2]1[C:3]([F:12])=[C:4]([CH:8]=[CH:9][C:10]=1[F:11])[C:5]([OH:7])=[O:6].[CH3:13][O:14]C1C(F)=C(Br)C=CC=1F>>[CH3:13][O:14][C:2]1[C:3]([F:12])=[C:4]([CH:8]=[CH:9][C:10]=1[F:11])[C:5]([OH:7])=[O:6]

Participants

3

Reactant 2

HCID 27735323-Chloro-2,4-difluorobenzoic acidHCID 183711091-Bromo-2,4-difluoro-3-methoxybenzene

Product 1

HCID 37805552,4-Difluoro-3-methoxybenzoic acid

Procedure

A procedure analogous to the 3-chloro-2,4-difluorobenzoic acid preparation is used starting from 3-methoxy-2,4-difluoro-bromobenzene.

Sources & evidence

ORD record
ord-df36a11d4ddd4dbf8378388d80c6e361
Source dataset
uspto-grants-2009_01
Patent number
US07482454B2

Reaction notes

Loading…