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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1455590Generated: November 4, 2026

Trifluoroacetic acid → HCID 68822405, compound

https://huagongshe.com/reaction/1455590

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant{1-[(5-Cyclopropyl-[1,3,4]oxadiazol-2-yl)-hydroxy-methyl]-propyl}-carbamic acid tert-butyl esterHCID 68822601—
SolventDichloromethaneHCID 6344—
ProductHCID 68822405HCID 68822405—

Reaction Steps

A mixture of {1-[(5-cyclopropyl-[1,3,4]oxadiazol-2-yl)-hydroxy-methyl]-propyl}-carbamic acid tert-butyl ester (2.83 g, 9.95 mmol), trifluoro acetic acid (5 mL) in dichloromethane (20 mL) is stirred at room temperature for 2 hrs and concentrated to dryness under reduced pressure to give (S)-2-amino-1-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-butan-1-ol: compound with trifluoro-acetic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07482448B2
Source datasetuspto-grants-2009_01
ORD IDord-83263ca7d82446d986ed9c4baa2e3e93
Source noteuspto-grants-2009_01