Sodium borohydride → HCID 57535417, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of aldehyde from step 2 in EtOH: THF (4:1, 0.05M) at 0° C. was added NaBH4 (1 eq). The reaction mixture was stirred 1 h at 0° C., quenched with a solution of NH4Cl and diluted with ether. The organic extracts were washed with brine, dried over Na2SO4, filtered and concentrated. The residue was purified by flash chromatography (hexane:EtOAc, 1:1 to 1:9) to afforded the title compound.

Provenance & Evidence