HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitric Acid → 5-bromo-6-nitro-2,3-dihydro-1H-inden-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | 5-Bromo-1-indanone | HCID 520695 | — |
| Product | 5-bromo-6-nitro-2,3-dihydro-1H-inden-1-one | HCID 53485149 | — |
Reaction Steps
Fuming nitric acid (166 ml) is cooled to −15° C., and 5-bromoindan-1-one (25 g, 0.118 mol) is then added portionwise. After stirring for 4 hours 30 minutes at between −10° C. and −15° C., the reaction mass is poured into ice-cold water (1600 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07482484B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-1dc8686ba03a42cc8bf847e84f4e13de |
| Source note | uspto-grants-2009_01 |