HCID 10473723, compound → HCID 9972074, compound

HRID 1455724Notes

Reaction equation

HRID 1455724 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9][C:10](=[O:23])/[CH:11]=[CH:12]/[C:13]2[CH:18]=[CH:17][C:16]([N+:19]([O-])=O)=[C:15]([F:22])[CH:14]=2)=[CH:5][C:4]=1[N+:24]([O-])=O>CC(C)=O.O>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9][C:10](=[O:23])/[CH:11]=[CH:12]/[C:13]2[CH:18]=[CH:17][C:16]([NH2:19])=[C:15]([F:22])[CH:14]=2)=[CH:5][C:4]=1[NH2:24]

Participants

3

Reactant 1

HCID 10473723HCID 10473723, compound

Product 1

HCID 9972074HCID 9972074, compoundYield 47%

Reagents, catalysts & solvents 1

HCID 18366337Propan-2-one--water (1/1)Solvent

Procedure

A solution of N-(4-methoxy-3-nitrophenyl)-3-(3-fluoro-4-nitropheny)-2-propenamide (Example 8) (1.3 mmol) in acetone-water (10:5) was reacted according to the procedure as described in the Example 6. The title compound, melting point 170-172° C., was thereby obtained in 47% yield.

Sources & evidence

ORD record
ord-2dfb8b677f054f1495df89012f3c92d0
Source dataset
uspto-grants-2009_01
Patent number
US07482488B2

Reaction notes

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