Boronic Acid → HCID 178440403, compound

HRID 1455744Notes

Reaction equation

HRID 1455744 reaction equation
Br[C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[C:4]([CH:11]([CH3:13])[CH3:12])=[N:5][NH:6]2.[BH:14]([OH:16])[OH:15]>>[CH:11]([C:4]1[C:3]2[C:2]([B:14]([OH:16])[OH:15])=[CH:10][CH:9]=[CH:8][C:7]=2[NH:6][N:5]=1)([CH3:13])[CH3:12]

Participants

3

Reactant 2

HCID 61668Boronic AcidHCID 1784404044-Bromo-3-isopropyl-1H-indazole

Product 1

HCID 178440403HCID 178440403, compound

Procedure

4-Bromo-3-isopropyl-1H-indazole is converted to the corresponding boronic acid following analogous procedures to that given in the preceding example. 1H NMR (CD3OD) 7.44(d, 1H), 7.32 (t, 1H), 7.05 (d, 1H), 3.56 (m, 1H), 1.38 (d, 6H). LCMS (m/z): 205.45 (MH)+.

Sources & evidence

ORD record
ord-3adec33be68748f59206e107b3c073eb
Source dataset
uspto-grants-2009_01
Patent number
US07482350B2

Reaction notes

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