HCID 9833644, compound → HCID 131720957, compound

Participants

Reaction Steps

This heterodimer of Isomer A from Example XI and CP-0597 was prepared by a similar coupling procedure as described in Example IV. The crude material was dissolved into 10% acetic acid/H2O and purified on RP-HPLC (90:10 to 35:65, H2O:CH3CN+0.1% TFA over 55 minutes) The desired fractions were combined, evaporated and lyophilized to give 18.4 mg of the fentanyl-CP-0597 heterodimer CP-0880 as a white powder.

Provenance & Evidence